In the entire HD group, there were no significant differences in circulating IFN-λ3 with respect to IFNL3 SNPs (Table 4), and patients with favourable outcomes did not differ in distribution of IFNL3 SNPs compared with subjects with unfavourable outcomes, although some association was suggested by the Pgenotype (Table 5). The gene discussed is IFNL3; the disease is Huntington disease.