ADAM10 and pulmonary arterial hypertension: JAG1 and ADAM10 are indispensable components of Notch signaling pathway, which were predicted as downstream targets of miR‐140‐5p in our analysis, suggesting that lack of miR‐140‐5p might promote the development of PAH by upregulation of JAG1 and ADAM10 genes and therefore activation of Notch3 cascade.