This finding is very interesting, because RAS mutation genes have been observed with variable frequencies (~15%–20%) in AML [54] and RAS mutations in early-age leukaemia were modulated by NQO1 rs1800566 (C609T), emphasizing the critical role of genetic susceptibility with somatic mutations in the mechanistic pathway leading to leukaemia in childhood [55]. The gene discussed is NQO1; the disease is leukemia.