Over 150 sarcoma subtypes have been analyzed for PD-L1 tumor expression and the presence of PD-1+ tumor-infiltrating lymphocytes (TILs): up to 65% of sarcomas expressed PD-L1 which, along with PD-1 TIL positivity, correlates with poorer overall survival and aggressive tumor features [47]. The gene discussed is CD274; the disease is neoplasm.