In our model, activation of cancer-related pathways were related to increased expression of Anxa2 important for angiogenesis24, Lgals3 overexpressed in lung cancers26 and tumor growth factor b receptor 2 (Tgfbr2) and Wnt5b, likely indicative of an increased TGFβ and Wnt signaling. Here, TGFB1 is linked to cancer.