CSNK1A1 and cancer: Moreover, an increasing number of reports link altered CK1 expression or activity to cancer (Knippschild et al., 2005; Dolezal et al., 2010; Fuja et al., 2004; Lin et al., 2014; Modak and Chai, 2009; Rodriguez et al., 2012; Schittek and Sinnberg, 2014), indicating that regulation and control of CK1 activity is of high importance for cells.