NGS feasibility in this context is also confirmed by another recent work [117], where the authors show the possibility to detect with high sensitivity and specificity 568 mutations within six genes (EGFR, K/NRAS, BRAF, cKIT, PDGFRa) (SiRe panel) in cell-free DNA obtained from serum and blood samples from patients affected by mCRC, non-small cell lung cancer (NSCLC) and melanoma. This evidence concerns the gene NRAS and non-small cell lung carcinoma.