Our results showed statistically significant correlation between positive/high expression of cyclin B1 and 5-year OS of patients with EC and CRC, with the pooled OR being 0.20 [95% CI 0.12–0.34; P < 0.00001] and 2.01 [95% CI 1.32–3.08; P = 0.001], respectively (Figures 5 and 6). The gene discussed is CCNB1; the disease is colorectal carcinoma.