Unsupervised clustering identified two stable clusters in DNA methylation (M1, M2) (Supplementary Figure 9B), mRNA (m1, m2) (Supplementary Figure 9A), miRNA (mi1, mi2) (Supplementary Figure 9C) and lncRNA (lnc1, lnc2) (Supplementary Figure 9D) expression data from 23 IDH wild-type astrocytoma samples. The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).