FOXO1 and neoplasm: In the 276 tumor tissue samples, negative expression of FOXO1 was found in 150 cases, weakly positive in 34 cases, moderate level in 62 cases, and strongly positive in 30 cases; negative expression of FOXO3 was found in 134 cases, weakly positive in 44 cases, moderately positive in 36 cases, and strongly positive in 62 cases; negative expression of FOXO4 was found in 118 cases, weakly positive in 60 cases, moderately positive in 52 cases, and strongly positive in 46 cases.