In the 276 tumor tissue samples, negative expression of FOXO1 was found in 150 cases, weakly positive in 34 cases, moderate level in 62 cases, and strongly positive in 30 cases; negative expression of FOXO3 was found in 134 cases, weakly positive in 44 cases, moderately positive in 36 cases, and strongly positive in 62 cases; negative expression of FOXO4 was found in 118 cases, weakly positive in 60 cases, moderately positive in 52 cases, and strongly positive in 46 cases. This evidence concerns the gene FOXO3 and neoplasm.