Although the role of TGFβ isoforms in tumors remains debatable [38–40], most studies that focus on exosomal TGFβ report that TGFβ1 enhances EMT in diverse cancer models [34–36], and TGFβ2 in milk exosomes drives breast cancer cells towards EMT [27]. The gene discussed is TGFB1; the disease is breast cancer.