TRPM8 and glioblastoma: To analyze possible anti-apoptotic functions of TRPM8, we compared in flow cytometry experiments the dissipation of the inner mitochondrial membrane potential (ΔΨm) and caspase activity as a measure of intrinsic apoptosis triggering and execution, respectively, between control (0 Gy) or irradiated (4 Gy) nt- and TRPM8 siRNA-transfected U251 and T98G glioblastoma cells (Figure 4).