Furthermore, lower Ang-1 (fold change = 0.73) and Tie-2 (fold change = 0.27) transcript levels and higher increases of miR-21-5p, miR27a-3p and miR-181a-5p (3.01 to 5.12- fold) levels were found in the rarest form of pancreatic carcinoma (Figure 1B). This evidence concerns the gene ANGPT1 and exocrine pancreatic carcinoma.