Recently, we provided evidence of EBV persistence and reactivation in B cells and plasma cells of hyperplastic and involuted thymuses from MG patients, but not in normal control thymuses, suggesting that the virus might be involved in the intra-thymic MG autoimmune process, likely through the activation and immortalization of autoreactive B cells and induction of pathogenic TLR7 and 9 signaling [24–26]. Here, TLR7 is linked to myasthenia gravis.