Since TLR3 has been reported to induce thymic overexpression of the AChR-alpha subunit and promote an anti-AChR autoimmune response [60], the identification of a positive correlation between TLR3 and EBER1 supports the hypothesis of a contribution of EBV to B cell-mediated autoimmunity via TLR3 in MG thymomas. This evidence concerns the gene TLR3 and myasthenia gravis.