CDC73 and tumor of parathyroid gland: The hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an autosomal dominant disorder characterized by occurrence of parathyroid tumors, atypical adenomas and carcinomas, ossifying jaw fibromas, renal tumors and uterine benign and malignant neoplasms, and caused by HRPT2 (also called CDC73) mutation.