The hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an autosomal dominant disorder characterized by occurrence of parathyroid tumors, atypical adenomas and carcinomas, ossifying jaw fibromas, renal tumors and uterine benign and malignant neoplasms, and caused by HRPT2 (also called CDC73) mutation. This evidence concerns the gene CDC73 and ossifying fibroma of the jaw.