Some studies have reported that some lncRNAs such as H19, HOTAIR, HOTTIP, MALAT1,PVT1,ENST00000480739,Gas5,AF339813,LOC389641,AFAP1-AS1, BC008363, GAS,HMlincRNA717,HOTAIRM1,HULU [11–19] are most closely associated with PC. This evidence concerns the gene MALAT1 and pachyonychia congenita.