In accordance, an analysis comparing CN-AML cases with 3p CDR (n = 9) with CN-AML without 3p deletion (n = 161) revealed a significant enrichment of gene sets associated with cancer, DNA repair as well as cell death and survival, which further supports a strong impact of PPP4R2 in 3p deleted AML (Supplementary Table 4). This evidence concerns the gene PPP4R2 and cancer.