KLK3 and Familial prostate cancer: We grouped the patients based on stage of prostate cancer (localized prostate cancer [stage ≤pT2c], local advanced prostate cancer [stage ≥pT3a]), Gleason score (Gleason score<7, Gleason score=7, Gleason score>7) and PSA value (PSA< ng/mL and PSA≥4 ng/mL).