BDNF and Anxiety: Based on findings of others regarding altered contextual learning in distress disorder, a process inherent of reinforcement learning, as well as prior observations pertaining to the potential involvement of BDNF in mood disorders and anxiety (Latsko et al., 2016; Levada et al., 2016; Cagni et al., 2017) assessing the presence and/or severity of distress disorder is feasible.