We found 2040 coding transcripts and 488 miRNAs differentially expressed between CALR-mutated vs. JAK2V617F-positive ET CD34+ cells, which can distinguish ET patients based on their mutational status (Fig. 1c, d, Supplementary Tables 1 and 2), while we were unable to identify any modulated genes in the pairwise comparison between PV and JAK2V617F-positive ET samples. This evidence concerns the gene CALR and essential thrombocythemia.