IL11 and Crohn disease: For example, recombinant IL-11 can ameliorate inflammatory diseases, such as psoriasis,15 heart disease,16 periodontal disease17 and Crohn’s disease.18 Moreover, IL-11 can modulate cytokine production from activated Th1 cells and diminish the polarization of the type 1 response.19 These results suggest that IL-11 likely has a general therapeutic potential in diseases where the Th1 responses are essential.