Interestingly, increased expression of these markers was also associated with higher expression of MYOCARDIN, a co‐transcription factor shown to upregulate expression of myofibroblast markers in hepatic stellate cells during liver fibrosis (Shimada & Rajagopalan, 2012), hence, indicating role of myocardin in mediating effect of FoxO3 in regulating myofibroblast differentiation in pulmonary fibrosis. This evidence concerns the gene FOXO3 and pulmonary fibrosis.