MiR-29a, accompanied with other tumor-suppressive miRNAs, such as miR-26a/b, miR-29b/c, and miR-218, apparently inhibited the migration and invasion of head and neck squamous cell carcinoma (HNSCC), via directly up-regulating LOXL2 [98]. This evidence concerns the gene LOXL2 and head and neck squamous cell carcinoma.