PSAT1 and neoplasm: As shown in the Fig. 5e and f, the in vivo tumor volume and weight of BT-549 cells was significantly increased from 218.3 ± 40.28 mm3 to 877.0 ± 81.04 mm3 (p < 0.0001) and from 0.2000 ± 0.03651 g to 0.7833 ± 0.07032 g (p < 0.0001) respectively, when PSAT1 was overexpressed.