HMOX1 and pachyonychia congenita: In situ hybridization of miR-193a-5p, combined with HO-1 immunostaining for the BPH and PC tissues, confirmed that the expression of miR-193a-5p and HO-1 was higher in the PC tissues than in BPH tissues (Fig. 3c) and that both miR-193a-5p and HO-1 were co-localizated in the PC tissues.