PKCα and FOXC2 are expressed in all endocrine resistant and basal TNBC (A and B) cell lines and among ER+ breast cancer cell lines, the endocrine resistant cells (T47D:C42, MCF7/PKCα, MCF7:TAM1, and MCF7:5C) have higher expression of PKCα compared to their endocrine sensitive counterparts T47D:A18 and MCF7 (Fig. 2a). Here, PRKCA is linked to breast cancer.