Both MMTV-PyMT.CCR5+/+ and MMTV-PyMT.CCR5−/− tumors were identified as high grade adenocarcinomas with nuclear pleomorphism, high mitotic count (mitotic index for MMTV-PyMT.CCR5+/+ tumors = 17 ± SEM 2; mitotic index for MMTV-PyMT.CCR5−/− tumors = 13 ± SEM 2) and low tubule formation (Fig. 2d, e). The gene discussed is CCR5; the disease is adenocarcinoma.