TPT1 and cancer: Histamine-Releasing Factor (HRF), also referred to as Translationally Controlled Tumour Protein (TCTP), p21, p23 and fortilin, is ubiquitously expressed in eukaryotes, and involved in apoptosis, cell cycle progression, cell proliferation and cancer (Bommer and Thiele, 2004, Nagano-Ito and Ichikawa, 2012, Bommer, 2012).