CD8A and metabolic dysfunction-associated steatohepatitis: For example, in a model of murine fibrosis induced by nonalcoholic steatohepatitis (NASH), hepatic CD11c+ DCs are able to limit CD8+ T cells expansion, produce elevated immune-modulatory cytokines—such as IL-6 and TNFα, but interestingly not IL-10—and activate CD4+ T cells [111], hence modulating hepatitis and fibrosis in NASH.