Transcriptomic profile analysis showed that two genes (L1CAM and FBN1) were upregulated and that four genes (AUST2, MAPT, AGT and USH1C) and two microRNAs (hsa-mir-100 and hsa-mir-378) were downregulated, all of which were associated with tumor malignancy. The gene discussed is FBN1; the disease is neoplasm.