OPTN and mild neurocognitive disorder: Mutations in the optineurin gene (OPTN) are known to cause openangle glaucoma, and more recently, mutations were identified in cases of ALS andFTD-MND.79 Variants inCHCHD10 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing10), a gene that encodes a mitochondrial protein, were recently identified in a fewfamilies with MND and FTD-MND.80