MAPT and Alzheimer disease: White matter tauopathy with globular glial inclusions and sporadic multiple systemtauopathy with dementia are rare forms of FTLD-tau characterized by 4R tau-positiveglobular glial (astrocytic and oligodendroglial) inclusions that some argue are thesame pathological entity.45 bvFTD,AD, PSP, CBS and MND have been reported as clinical phenotypes of patients diagnosedwith this condition.