Plasma IL-6 concentrations have been correlated with CT brain infarct volume (r=0.75)and mRS at 3 months (r=0.72).45IL-6 levels were also strongly associated with CRP levels and white blood cell (WBC)count.45 In the FraminghamOffspring Study, inflammatory biomarkers were associated with neuroimaging markersof ischemia and dementia (e.g. white matter hyperintensities and total brainvolume). Here, IL6 is linked to brain infarction.