Hypertension is associated to increased risk of dementia, and control withanti-hypertensives, mainly with angiotensin converting enzyme inhibitors, hasdemonstrated a significant reduction in the incidence of dementia.12 Diabetes is an independent predictorof risk of cognitive decline, and the metabolic syndrome, an important cardiovascularrisk factor, plays a role as a predictor of risk for dementia.17 This evidence concerns the gene ACE and dementia.