The AD group tended to have lower levels of average free testosterone (222.4 pmol/L,±101.8) than the control group (272.3 pmol/L, ±96.1) reaching aborderline statistical difference (p=0.06), and tended to have higher average levelsof SHBG 73.1 (SD±32.7) and 56.2 nmol/L (SD±26.8). This evidence concerns the gene SHBG and Alzheimer disease.