Although a specific marker, FDBS may be present in a minority of patients withanti-LGI1 encephalitis.11Antibodies against LGI1 were discovered in 2010.30,31 Before improvedcharacterization of this target, it was thought that the disease was caused byantibodies directed against voltage-gated potassium channels (VGKC). The gene discussed is LGI1; the disease is encephalitis.