Neuropathological diagnosticcriteria for CBD require tau inclusions in neurons and glia with astrocytic plaquesand extensive thread-like pathology.42 Like CBD, PSP has threads in gray and white matter, but in CBDthe boundary between gray and white matter may be indistinct due to the severity ofthreads in both compartments (Figure1).39,44,45. Here, MAPT is linked to supranuclear palsy, progressive, 1.