MAPT and Alzheimer disease: Additional assessment of [18F]THK-5105, conducted using [11C]PIB and AD hemibrain sections, observed dense accumulation of [18F]THK-5105 in tau-rich areas-including the hippocampus/parahippocampus, insula, cingulate gyrus and inferior and middle temporal gyri-with the pattern of tracer binding corresponding to the recognized distribution of tau pathology but not to that of Ab or areas showing elevated retention of [11C]PIB.