Other GLP-1 analogs have been reported to have an analgesic effect in both somatic and visceral pain states: ROSE-010 shows promising results in relieving visceral pain in patients suffering from IBS (295), while liraglutide suppresses the visceral hyperalgesia induced by LPS or water avoidance stress (WAS) in rats (296). The gene discussed is GCG; the disease is irritable bowel syndrome.