To determine how the phenotype of memory CD8 T cells generated following infection compares between inbred and outbred mice, we examined expression of CD127, CD62L, CD27, and KLRG1 among CD8hi/CD11alo Ag-inexperienced and CD8lo/CD11ahi Ag-experienced CD8 T cells at various times following LCMV infection. Here, CD8A is linked to infection.