C5AR1 and persistent truncus arteriosus: WGA demarcates the cell membrane of individual cells (Fig. 4a) and it showed a significant increase in cell size in WT mice (272 ± 40 μm2 in sham operated mice vs. 310 ± 27 in TAC mice, p = 0.0355, Fig. 4b) and a trend towards an increase in C5aR−/− mice (280 ± 28 μm2 in sham operated mice vs. 317 ± 43 μm2 in TAC mice, p = 0.0828, Fig. 4b) upon 6 weeks of TAC.