FCGR2A and autoimmune thrombocytopenic purpura: FcγRs have been directly linked to a number of diseases such as immune thrombocytopenia purpura (ITP), through FcγR-mediated platelet phagocytosis by splenic and liver macrophages, and myasthenia gravis, potentially through the destruction of AChR-expressing cells by antibody-dependent cell-mediated cytotoxicity5.