LGALS3 and infection: Since augmented Gal3 expression was previously reported during human and experimental inflammatory diseases26, 27, we determined Gal-3 levels in tissues and serum of C57BL/6 mice on days 3, 7, and 14 post-infection with C. neoformans. In comparison with control animals, infected mice had higher Gal-3 levels in all examined tissues and serum samples (Fig. 1).