LGALS3 and candidiasis: These showed Gal-3 participation24, 34, 39 in the generation of Th17 protective immunity against candidiasis (reviewed by ref. 40), a phenomenon verified in this study for C. neoformans. The studies on experimental candidiasis revealed also that interaction with Gal-3 is responsible for several macrophages responses previously reported as stimulated by β-1,2-linked oligomannosides of C. albicans41.