TNFRSF11B and myeloid sarcoma: The rs2073618 variant (OPG, chromosome 8 position 119,964,052, minor (G) allele frequency = 0.49, HWE P = 0.50) was not significantly associated with change in MS symptom cluster (P = 0.134) or any secondary phenotypes (all P > 0.05, Table 2).