Therefore, the treatment focused on Rab27a gene could target multiple aspects of tumor treatment, for example, it could selectively increase the enzymatic activity of apoptosis gene and/or inhibit the expression of anti hole of apoptosis genes in tumor cells, strengthen the efficacy of chemotherapy or radiotherapy and reduce the toxic and side effects [28–30], thus provide a new reference for clinical chemotherapy drugs. This evidence concerns the gene RAB27A and neoplasm.