Although univariate analyses showed that several factors were significantly associated with OS (p<0.05 each), multivariate analysis showed that Child-Pugh classification, serum level of AFP, status of intrahepatic tumor, number of metastatic LNs, location of metastatic LNs, presence of distant metastasis, and LN response were independently associated with OS (p<0.05 each). Here, AFP is linked to neoplasm.