Subsequent cell viability assays performed on DDP-resistant lung cancer cells (A549/DDP and H1299/DDP) showed that MALAT1 knockdown reduced the lC50 values for both A549/DDP and H1299/DDP cells, indicating MALAT1 knockdown sensitizes DDP-resistant lung cancer cells to DDP. This evidence concerns the gene MALAT1 and lung carcinoma.