GAPDH and cancer: Thus, cancer-specific energy metabolism pathways might be a target for cancer chemotherapy; for example, 2-deoxyglucose (a hexokinase inhibitor) and 3-bromopyruvate (a dual inhibitor of hexokinase and glyceraldehyde 3-phosphate dehydrogenase) suppress proliferation of cancer cells in vitro by inhibiting the glycolytic pathway [18, 19].