WWTR1 and adrenal cortex carcinoma: Whereas single knockdown of YAP1 or TAZ did not decrease cell proliferation in our system, concomitant knockdown of YAP1 and TAZ decreased cell proliferation significantly (41%, 43%, and 46% decrease in ACC-MESO-4, NCI-H28, and Y-MESO-27, respectively) (Supplementary Figure 3A).