HMMR and liver cancer: Beside CD44, receptor for hyaluronic acid-mediated motility (RHAMM, also known as HMMR, IHABP or CD168) functions as a HA receptor [28], and several studies have shown that aberrant expression of RHAMM, which is generally not detected in normal tissues, is involved in cell proliferation, migration, invasion and drug resistance in several tumors including breast [13], lung [29], and liver cancers [30].