Left-sided colorectal cancer (LCRC) is more common in men, and associated with familial adenomatous polyposis syndrome, Wnt and EGFR signaling, chromosomal instability, ERBB1 and ERBB2 amplifications, and APC, p53, and NRAS mutations [10, 11]. Here, EGFR is linked to Familial adenomatous polyposis.